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1415329-20-2

1415329-20-2 structure
1415329-20-2 structure
  • Name: Ald-CH2-PEG4-Boc
  • Chemical Name: Ald-PEG4-t-butyl ester
  • CAS Number: 1415329-20-2
  • Molecular Formula: C15H28O7
  • Molecular Weight: 320.379
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-02 07:47:15
  • Modify Date: 2024-01-06 17:05:26
  • Ald-CH2-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Ald-PEG4-t-butyl ester
Synonyms ALD-CH2-PEG4-T-BUTYL ESTER
Description Ald-CH2-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Boiling Point 401.7±35.0 °C at 760 mmHg
Molecular Formula C15H28O7
Molecular Weight 320.379
Flash Point 173.2±26.0 °C
Exact Mass 320.183502
LogP 0.08
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.445