Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: N-BIOTINYL-N'-MALEIMIDO-ETHYLENEDIAMINE
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Purity: 98.0%
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139554-72-6

139554-72-6 structure

139554-72-6 structure

Name: N-BIOTINYL-N'-MALEIMIDO-ETHYLENEDIAMINE
Chemical Name: N-BIOTINYL-N'-MALEIMIDO-ETHYLENEDIAMINE
CAS Number: 139554-72-6
Molecular Formula: C₁₆H₂₃N₅O₄S
Molecular Weight: 381.45
Catalog: Research Areas Cancer
Create Date: 2018-06-25 00:10:29
Modify Date: 2024-01-19 15:14:40
Biotin-C2-maleimide is an antibody conjugate reagent, can bind to many biomolecules without significantly changing the biological activity of the target molecule[1][2].

Name	N-BIOTINYL-N'-MALEIMIDO-ETHYLENEDIAMINE

Description	Biotin-C2-maleimide is an antibody conjugate reagent, can bind to many biomolecules without significantly changing the biological activity of the target molecule[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	Biotin-C2-maleimide () can act bioconjugation with 5 eq. SUMO-1 probes[1]. 1. Biotin C2 maleimide (ATT Bioquest, dissolved in DMSO) is performed in Tris buffer (50 mM Tris, 300 mM NaCl; pH 7.0) after 15 min reduction with Tris (2-carboxyethyl)phosphine (TCEP, 120 µM) at room temperature. 2. After 1 h incubation, the unreacted Biotin is separated by Ni-NTA affinity chromatography followed by dialysis against PBS buffer (pH 7.4).
References	[1]. Benjamin GD, et al. Antibody conjugates and methods of making the antibody conjugates: United States, US20160361436A1. 2016-12-15. [2]. Brüninghoff K, Wulff S, Dörner W, Geiss-Friedlander R, Mootz HD. A Photo-Crosslinking Approach to Identify Class II SUMO-1 Binders. Front Chem. 2022 May 30;10:900989.

Melting Point	123-129°C
Molecular Formula	C₁₆H₂₃N₅O₄S
Molecular Weight	381.45
Storage condition	-20°C Freezer, Under Inert Atmosphere