1233234-77-9

1233234-77-9 structure
1233234-77-9 structure
  • Name: Boc-NH-PEG11-NH2
  • Chemical Name: Boc-NH-PEG11-CH2CH2NH2
  • CAS Number: 1233234-77-9
  • Molecular Formula: C29H60N2O13
  • Molecular Weight: 644.792
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-11-10 12:19:54
  • Modify Date: 2025-08-27 08:56:21
  • Boc-NH-PEG11-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Boc-NH-PEG11-CH2CH2NH2
Synonyms Boc-PEG-amine (n=11)
2-Methyl-2-propanyl (35-amino-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacont-1-yl)carbamate
MFCD03453245
Carbamic acid, N-(35-amino-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacont-1-yl)-, 1,1-dimethylethyl ester
Description Boc-NH-PEG11-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Boiling Point 667.6±55.0 °C at 760 mmHg
Molecular Formula C29H60N2O13
Molecular Weight 644.792
Flash Point 357.5±31.5 °C
Exact Mass 644.409546
LogP -3.03
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.467
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.