834919-19-6

834919-19-6 structure

Name: Edoxaban M4
Chemical Name: D21-2393
CAS Number: 834919-19-6
Molecular Formula: C₂₂H₂₅ClN₆O₅S
Molecular Weight: 520.99
Catalog: Research Areas Metabolic Disease
Create Date: 2018-06-25 23:31:16
Modify Date: 2024-01-06 17:08:15
Edoxaban M4, an active metabolite of Edoxaban, shows reproducible, but concentration-dependent matrix effects. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor [1][2].

Name	D21-2393
Synonyms	D21-2393 Cyclohexanecarboxylic acid, 4-[[2-[(5-chloro-2-pyridinyl)amino]-1,2-dioxoethyl]amino]-3-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]-, (1S,3R,4S)- IV344R972X (1S,3R,4S)-4-({[(5-Chloro-2-pyridinyl)amino](oxo)acetyl}amino)-3-{[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbonyl]amino}cyclohexanecarboxylic acid

Description	Edoxaban M4, an active metabolite of Edoxaban, shows reproducible, but concentration-dependent matrix effects. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor [1][2].
Related Catalog	Research Areas >> Metabolic Disease
References	[1]. Romain Siriez, et al. Importance of measuring pharmacologically active metabolites of edoxaban: development and validation of an ultra-high-performance liquid chromatography coupled with a tandem mass spectrometry method. J Thromb Thrombolysis. 2020 Apr;49(3):395-403. [2]. Kathrin I Foerster, et al. Simultaneous quantification of direct oral anticoagulants currently used in anticoagulation therapy. J Pharm Biomed Anal. 2018 Jan 30;148:238-244.