156159-18-1

156159-18-1 structure

Name: Lys-γ3-MSH(human)
Chemical Name: L-Lysyl-L-tyrosyl-L-valyl-L-methionylglycyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl-L-α-aspartyl-L-arginyl-L-phenylalanylglycyl-L-arginyl-L-arginyl-L-asparaginyl-L-seryl-L-seryl-L-seryl-L-serylglycyl-L-seryl-L-serylglycyl-L-alanylglycyl-L-glutamine
CAS Number: 156159-18-1
Molecular Formula: C₁₂₈H₁₉₃N₄₅O₃₉S
Molecular Weight: 3018.245
Catalog: Research Areas Endocrinology
Create Date: 2018-06-10 17:33:46
Modify Date: 2025-08-24 18:21:45
Lys-γ3-MSH(human) is a melanocortin peptide derived from the C-terminal of the fragment of pro-opiomelanocortin (POMC). Lys-γ3-MSH(human) potentiates the steroidogenic response of the rat adrenal to adrenocorticotrophin (ACTH). Lys-γ3-MSH(human) is a potent stimulator of lipolysis with an apparent EC50 of 3.56 nM. Lys-γ3-MSH(human) can activate hormone sensitive lipase (HSL) and Perilipin A resulting in lipolysis[1][2].

Name	L-Lysyl-L-tyrosyl-L-valyl-L-methionylglycyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl-L-α-aspartyl-L-arginyl-L-phenylalanylglycyl-L-arginyl-L-arginyl-L-asparaginyl-L-seryl-L-seryl-L-seryl-L-serylglycyl-L-seryl-L-serylglycyl-L-alanylglycyl-L-glutamine
Synonyms	L-Lysyl-L-tyrosyl-L-valyl-L-methionylglycyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl-L-α-aspartyl-L-arginyl-L-phenylalanylglycyl-L-arginyl-L-arginyl-L-asparaginyl-L-seryl-L-seryl-L-seryl-L -serylglycyl-L-seryl-L-serylglycyl-L-alanylglycyl-L-glutamine L-Glutamine, L-lysyl-L-tyrosyl-L-valyl-L-methionylglycyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl-L-α-aspartyl-L-arginyl-L-phenylalanylglycyl-L-arginyl-L-arginyl-L-asparaginyl-L-seryl-L-se ryl-L-seryl-L-serylglycyl-L-seryl-L-serylglycyl-L-alanylglycyl-

Description	Lys-γ3-MSH(human) is a melanocortin peptide derived from the C-terminal of the fragment of pro-opiomelanocortin (POMC). Lys-γ3-MSH(human) potentiates the steroidogenic response of the rat adrenal to adrenocorticotrophin (ACTH). Lys-γ3-MSH(human) is a potent stimulator of lipolysis with an apparent EC50 of 3.56 nM. Lys-γ3-MSH(human) can activate hormone sensitive lipase (HSL) and Perilipin A resulting in lipolysis[1][2].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> Others >> Others
References	[1]. Harmer SC, Pepper DJ, Cooke K, Bennett HP, Bicknell AB. Evidence of a possible role for Lys-gamma3-MSH in the regulation of adipocyte function. J Endocrinol. 2008;196(1):149-158. [2]. Bicknell KA, et al. Lys-gamma3-MSH: a global regulator of hormone sensitive lipase activity?. Mol Cell Endocrinol. 2009;300(1-2):71-76.