322455-70-9
322455-70-9 structure
- Name: FSL-1
- Chemical Name: S-[(2R)-2,3-Bis(palmitoyloxy)propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-L-phenylalanine
- CAS Number: 322455-70-9
- Molecular Formula: C84H140N14O18S
- Molecular Weight: 1666.158
- Catalog: Signaling Pathways Immunology/Inflammation Toll-like Receptor (TLR)
- Create Date: 2018-06-10 12:56:03
- Modify Date: 2024-01-03 19:48:26
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FSL-1 is a TLR2/6 agonist (also a putative TLR10 ligand). FSL-1 activates NF-κB. FSL-1 induces pro-inflammatory cytokines including IL-8, IL-1β, CCL20 and TNF-α in vitro. FSL-1 synergizes with IFNγ to induce CXCL10 release from melanoma cells.
| Name | S-[(2R)-2,3-Bis(palmitoyloxy)propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-L-phenylalanine |
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| Synonyms |
S-[(2R)-2,3-Bis(palmitoyloxy)propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-L-phenylalanine
L-Phenylalanine, S-[(2R)-2,3-bis[(1-oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl- |
| Description | FSL-1 is a TLR2/6 agonist (also a putative TLR10 ligand). FSL-1 activates NF-κB. FSL-1 induces pro-inflammatory cytokines including IL-8, IL-1β, CCL20 and TNF-α in vitro. FSL-1 synergizes with IFNγ to induce CXCL10 release from melanoma cells. |
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| Related Catalog |
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 1659.8±65.0 °C at 760 mmHg |
| Molecular Formula | C84H140N14O18S |
| Molecular Weight | 1666.158 |
| Flash Point | 957.6±34.3 °C |
| Exact Mass | 1665.019043 |
| LogP | 15.83 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.553 |
| RIDADR | NONH for all modes of transport |
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