478941-93-4

478941-93-4 structure

Name: Budiodarone tartrate
Chemical Name: Budiodarone tartrate
CAS Number: 478941-93-4
Molecular Formula: C₃₁H₃₇I₂NO₁₁
Molecular Weight: 853.435
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Calcium Channel
Create Date: 2018-06-23 15:54:57
Modify Date: 2024-01-08 07:11:28
Budiodarone (ATI-2042) tartrate is a chemical analogue of Amiodarone (HY-14187) with balanced, multiple cardiac ion channel (potassium, sodium and calcium channels) inhibiting activity. Budiodarone tartrate is an antiarrhythmic agent[1].

Name	Budiodarone tartrate
Synonyms	(2R,3R)-2,3-Dihydroxysuccinic acid - (2S)-2-butanyl (3-{4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl}-1-benzofuran-2-yl)acetate (1:1) Budiodarone tartrate 2-Benzofuranacetic acid, 3-[4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl]-, (1S)-1-methylpropyl ester, compd. with (2R,3R)-2,3-dihydroxybutanedioic acid (1:1) 3HV5H0W9GM

Description	Budiodarone (ATI-2042) tartrate is a chemical analogue of Amiodarone (HY-14187) with balanced, multiple cardiac ion channel (potassium, sodium and calcium channels) inhibiting activity. Budiodarone tartrate is an antiarrhythmic agent[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Research Areas >> Cardiovascular Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
In Vitro	Budiodarone (ATI-2042) tartrate 血浆半衰期短 (7 h)，分布体积小 (13 L/kg)[1]。
References	[1]. Ezekowitz MD, et al. A randomized trial of budiodarone in paroxysmal atrial fibrillation. J Interv Card Electrophysiol. 2012 Jun;34(1):1-9.