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1334177-84-2

1334177-84-2 structure
1334177-84-2 structure
  • Name: Hydroxy-PEG8-Boc
  • Chemical Name: 2-Methyl-2-propanyl 1-hydroxy-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate
  • CAS Number: 1334177-84-2
  • Molecular Formula: C23H46O11
  • Molecular Weight: 498.605
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-08 02:25:43
  • Modify Date: 2024-01-10 07:14:01
  • Hydroxy-PEG8-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Name 2-Methyl-2-propanyl 1-hydroxy-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate
Synonyms 2-Methyl-2-propanyl 1-hydroxy-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate
3,6,9,12,15,18,21,24-Octaoxaheptacosan-27-oic acid, 1-hydroxy-, 1,1-dimethylethyl ester
Description Hydroxy-PEG8-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Density 1.1±0.1 g/cm3
Boiling Point 549.5±45.0 °C at 760 mmHg
Molecular Formula C23H46O11
Molecular Weight 498.605
Flash Point 168.6±22.2 °C
Exact Mass 498.304016
LogP -1.81
Vapour Pressure 0.0±3.4 mmHg at 25°C
Index of Refraction 1.459
Storage condition 2-8°C