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581066-04-8

581066-04-8 structure
581066-04-8 structure
  • Name: Azido-PEG4-Boc
  • Chemical Name: 2-Methyl-2-propanyl 1-azido-3,6,9,12-tetraoxapentadecan-15-oate
  • CAS Number: 581066-04-8
  • Molecular Formula: C15H29N3O6
  • Molecular Weight: 347.407
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-08 14:21:50
  • Modify Date: 2024-01-14 17:57:07
  • Azido-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 2-Methyl-2-propanyl 1-azido-3,6,9,12-tetraoxapentadecan-15-oate
Synonyms 2-Methyl-2-propanyl 1-azido-3,6,9,12-tetraoxapentadecan-15-oate
3,6,9,12-Tetraoxapentadecan-15-oic acid, 1-azido-, 1,1-dimethylethyl ester
Azido-PEG5-t-butyl ester
Description Azido-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C15H29N3O6
Molecular Weight 347.407
Exact Mass 347.205627
LogP 0.63
Storage condition 2-8°C