1572583-29-9

1572583-29-9 structure

Name: Teneligliptin hydrobromide hydrate
Chemical Name: Teneligliptin sesquihydrobromide hydrate
CAS Number: 1572583-29-9
Molecular Formula: C₂₂H₃₀N₆OS
Molecular Weight: 1275.731
Catalog: Signaling Pathways Metabolic Enzyme/Protease Dipeptidyl Peptidase
Create Date: 2018-06-06 11:07:00
Modify Date: 2025-08-27 11:01:19
Teneligliptin hydrobromide hydrate is a potent chemotype prolylthiazolidine-based DPP-4 inhibitor, which competitively inhibits human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50s of approximately 1 nM[1].

Name	Teneligliptin sesquihydrobromide hydrate
Synonyms	Teneligliptin sesquihydrobromide hydrate Methanone, [(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-1-piperazinyl]-2-pyrrolidinyl]-3-thiazolidinyl-, hydrobromide, hydrate (2:5:1) {(2S,4S)-4-[4-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)-1-piperazinyl]-2-pyrrolidinyl}(1,3-thiazolidin-3-yl)methanone hydrobromide hydrate (2:5:1)

Description	Teneligliptin hydrobromide hydrate is a potent chemotype prolylthiazolidine-based DPP-4 inhibitor, which competitively inhibits human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50s of approximately 1 nM[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Dipeptidyl Peptidase Research Areas >> Metabolic Disease
References	[1]. Fukuda-Tsuru S, et al. A novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor, teneligliptin, improves postprandial hyperglycemia and dyslipidemia after single and repeated administrations. Eur J Pharmacol. 2012 Dec 5;696(1-3):194-202.