1616080-84-2

1616080-84-2 structure

Name: Hispidanin B
Chemical Name: (4aR,5S,8aS)-5-{[(1S,2S,4'S,5a'S,9a'S)-4'-Acetoxy-3,6',6',9a'-tetramethyl-2'-oxo-4',5',5a',6',7',8',9',9a'-octahydrospiro[cyclohex-3-ene-1,3'-phenanthro[2,1-b]furan]-2-yl]methyl}-1,1-dimethyl-6-methyleneoctahydro-4a(2H)-naphthalenecarboxylic acid
CAS Number: 1616080-84-2
Molecular Formula: C₄₂H₅₆O₆
Molecular Weight: 656.89
Create Date: 2018-07-01 17:52:14
Modify Date: 2024-01-05 09:46:51
Hispidanin B is a natural product that can be extracted from the rhizomes of Isodon hispida. Hispidanin B has cytotoxic activities against cancer cells[1].

Name	(4aR,5S,8aS)-5-{[(1S,2S,4'S,5a'S,9a'S)-4'-Acetoxy-3,6',6',9a'-tetramethyl-2'-oxo-4',5',5a',6',7',8',9',9a'-octahydrospiro[cyclohex-3-ene-1,3'-phenanthro[2,1-b]furan]-2-yl]methyl}-1,1-dimethyl-6-methyleneoctahydro-4a(2H)-naphthalenecarboxylic acid
Synonyms	4a(2H)-Naphthalenecarboxylic acid, 5-[[(1S,2S,4'S,5a'S,9a'S)-4'-(acetyloxy)-4',5',5'a,6',7',8',9',9'a-octahydro-3,6',6',9'a-tetramethyl-2'-oxospiro[cyclohex-3-ene-1,3'(2'H)-phenanthro[2,1-b]furan]-2-yl]methyl]octahydro-1,1-dimethyl-6-methylene-, (4aR,5S,8aS)- (4aR,5S,8aS)-5-{[(1S,2S,4'S,5a'S,9a'S)-4'-Acetoxy-3,6',6',9a'-tetramethyl-2'-oxo-4',5',5a',6',7',8',9',9a'-octahydrospiro[cyclohex-3-ene-1,3'-phenanthro[2,1-b]furan]-2-yl]methyl}-1,1-dimethyl-6-methyleneoctahydro-4a(2H)-naphthalenecarboxylic acid Hispidanin B

Description	Hispidanin B is a natural product that can be extracted from the rhizomes of Isodon hispida. Hispidanin B has cytotoxic activities against cancer cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	Hispidanin B 对 SGC7901、SMMC7721 和 K562 具有细胞毒活性，IC50 值分别为 10.7、9.8 和 13.7 μM[1]。
References	[1]. Huang B, et al. Hispidanins A-D: four new asymmetric dimeric diterpenoids from the rhizomes of Isodon hispida. Org Lett. 2014 Jul 3;16(13):3552-5.