1215767-66-0

1215767-66-0 structure

Name: Ketorolac D5
Chemical Name: 5-[(2H5)Phenylcarbonyl]-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
CAS Number: 1215767-66-0
Molecular Formula: C₁₅H₈D₅NO₃
Molecular Weight: 260.299
Catalog: Signaling Pathways Immunology/Inflammation COX
Create Date: 2018-07-06 06:46:48
Modify Date: 2024-01-04 02:03:26
Ketorolac D5 is a deuterium labeled Ketorolac. Ketorolac is a non-steroidal anti-inflammatory agent, acting as a nonselective COX inhibitor, with IC50s of 20 nM for COX-1 and 120 nM for COX-2[1].

Name	5-[(2H5)Phenylcarbonyl]-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
Synonyms	1H-Pyrrolizine-1-carboxylic acid, 2,3-dihydro-5-(phenyl-d5-carbonyl)- 5-[(2H5)Phenylcarbonyl]-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid

Description	Ketorolac D5 is a deuterium labeled Ketorolac. Ketorolac is a non-steroidal anti-inflammatory agent, acting as a nonselective COX inhibitor, with IC50s of 20 nM for COX-1 and 120 nM for COX-2[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> COX
Target	COX-1:20 nM (IC50) COX-2:120 nM (IC50)
References	[1]. Waterbury LD, et al. Comparison of cyclooxygenase inhibitory activity and ocular anti-inflammatory effects of ketorolac tromethamine and bromfenac sodium. Curr Med Res Opin. 2006 Jun;22(6):1133-40.