1263044-81-0
1263044-81-0 structure
- Name: m-PEG4-amino-Mal
- Chemical Name: 3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(2,5,8,11-tetraoxatridecan-13-yl)propanamide
- CAS Number: 1263044-81-0
- Molecular Formula: C16H26N2O7
- Molecular Weight: 358.387
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-18 17:39:09
- Modify Date: 2024-01-02 10:08:23
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m-PEG4-amino-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(2,5,8,11-tetraoxatridecan-13-yl)propanamide |
|---|---|
| Synonyms |
1H-Pyrrole-1-propanamide, 2,5-dihydro-2,5-dioxo-N-3,6,9,12-tetraoxatridec-1-yl-
3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(2,5,8,11-tetraoxatridecan-13-yl)propanamide |
| Description | m-PEG4-amino-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 548.7±50.0 °C at 760 mmHg |
| Molecular Formula | C16H26N2O7 |
| Molecular Weight | 358.387 |
| Flash Point | 285.6±30.1 °C |
| Exact Mass | 358.174011 |
| LogP | -2.06 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.499 |