1253286-56-4
1253286-56-4 structure
- Name: Biotin-PEG3-NHS ester
- Chemical Name: N-{2-[2-(2-{3-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy}ethoxy)ethoxy]ethyl}-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide
- CAS Number: 1253286-56-4
- Molecular Formula: C23H36N4O9S
- Molecular Weight: 544.618
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-07-03 22:09:45
- Modify Date: 2024-01-11 06:56:39
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Biotin-PEG3-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
| Name | N-{2-[2-(2-{3-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy}ethoxy)ethoxy]ethyl}-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide |
|---|---|
| Synonyms |
MFCD11974977
N-{2-[2-(2-{3-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy}ethoxy)ethoxy]ethyl}-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide 1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[2-[2-[2-[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy]ethoxy]ethoxy]ethyl]hexahydro-2-oxo-, (3aS,4S,6aR)- |
| Description | Biotin-PEG3-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTAC. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C23H36N4O9S |
| Molecular Weight | 544.618 |
| Exact Mass | 544.220276 |
| LogP | -2.93 |
| Index of Refraction | 1.574 |