1008402-47-8
1008402-47-8 structure
- Name: Bis-Mal-PEG3
- Chemical Name: N,N'-[Oxybis(2,1-ethanediyloxy-2,1-ethanediyl)]bis[3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide]
- CAS Number: 1008402-47-8
- Molecular Formula: C22H30N4O9
- Molecular Weight: 494.495
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-24 17:23:59
- Modify Date: 2024-01-09 17:45:50
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Bis-Mal-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | N,N'-[Oxybis(2,1-ethanediyloxy-2,1-ethanediyl)]bis[3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide] |
|---|---|
| Synonyms |
N,N'-[Oxybis(2,1-ethanediyloxy-2,1-ethanediyl)]bis[3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide]
1H-Pyrrole-1-propanamide, N,N'-[oxybis(2,1-ethanediyloxy-2,1-ethanediyl)]bis[2,5-dihydro-2,5-dioxo- |
| Description | Bis-Mal-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 791.7±60.0 °C at 760 mmHg |
| Molecular Formula | C22H30N4O9 |
| Molecular Weight | 494.495 |
| Flash Point | 432.6±32.9 °C |
| Exact Mass | 494.201294 |
| LogP | -2.61 |
| Vapour Pressure | 0.0±2.8 mmHg at 25°C |
| Index of Refraction | 1.549 |