1631137-51-3
1631137-51-3 structure
- Name: E3 ligase Ligand 6
- Chemical Name: E3 ligase Ligand 6
- CAS Number: 1631137-51-3
- Molecular Formula: C24H31F3N4O5S
- Molecular Weight: 544.59
- Catalog: Signaling Pathways PROTAC Ligand for E3 Ligase
- Create Date: 2018-02-12 06:04:58
- Modify Date: 2025-08-25 18:46:08
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Protein degrader 1 TFA is a small molecule ligand for VHL, an E3 ligase which has been targeted in numerous PROTACs.
| Name | E3 ligase Ligand 6 |
|---|
| Description | Protein degrader 1 TFA is a small molecule ligand for VHL, an E3 ligase which has been targeted in numerous PROTACs. |
|---|---|
| Related Catalog | |
| Target |
E3 ligase VHL[1] |
| In Vitro | Synthesis of HaloPROTACs contains Protein degrader 1 (Degradation Inducing Moiety A). Protein degrader 1 (Degradation Inducing Moiety A) is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays. HaloPROTACs containing Protein degrader 1 (Degradation Inducing Moiety A) lead to nearly 70% degradation of GFP-HaloTag7, when sufficiently long linkers are used[1]. |
| References |
| Molecular Formula | C24H31F3N4O5S |
|---|---|
| Molecular Weight | 544.59 |