1241826-88-9
1241826-88-9 structure
- Name: Soluble epoxide hydrolase inhibitor
- Chemical Name: Soluble epoxide hydrolase inhibitor
- CAS Number: 1241826-88-9
- Molecular Formula: C18H12F5N5O3
- Molecular Weight: 441.31
- Catalog: Research Areas Cardiovascular Disease
- Create Date: 2018-04-28 11:59:36
- Modify Date: 2024-01-04 20:06:10
-
Soluble epoxide hydrolase inhibitor is an inhibitor of soluble epoxide hydrolase, and inhibits human soluble epoxide hydrolase (h-sEH) with pIC50 of 8.4, extracted from patent WO 2010096722 A1, example 57.
| Name | Soluble epoxide hydrolase inhibitor |
|---|
| Description | Soluble epoxide hydrolase inhibitor is an inhibitor of soluble epoxide hydrolase, and inhibits human soluble epoxide hydrolase (h-sEH) with pIC50 of 8.4, extracted from patent WO 2010096722 A1, example 57. |
|---|---|
| Related Catalog | |
| Target |
pIC50: 8.4 (h-sEH)[1] |
| In Vitro | Soluble epoxide hydrolase inhibitor (Example 57) is an inhibitor of soluble epoxide hydrolase, and inhibits human soluble epoxide hydrolase with pIC50 of 8.4[1]. |
| Kinase Assay | The sEH inhibitory properties of test compounds (including Soluble epoxide hydrolase inhibitor) are determined using a black 384-well-plate format under the following reaction conditions: 20 mM Tris pH 7.0, 0.1 mM EDTA, 0.1 mg/mL BSA, 5 μM PHOME (substrate), 2 nM sEH enzyme, 1% DMSO (from test compound). Reaction product is determined quantitatively by fluorescence intensity using a Fluorescence plate reader with an excitation wavelength at 330 nm and emission at 465 nm[1]. |
| References |
| Molecular Formula | C18H12F5N5O3 |
|---|---|
| Molecular Weight | 441.31 |