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1817626-54-2

1817626-54-2 structure
1817626-54-2 structure
  • Name: PF06650833
  • Chemical Name: PF06650833
  • CAS Number: 1817626-54-2
  • Molecular Formula: C18H20FN3O4
  • Molecular Weight: 361.367
  • Catalog: Signaling Pathways Immunology/Inflammation IRAK
  • Create Date: 2018-03-30 12:14:29
  • Modify Date: 2024-01-09 20:43:01
  • PF06650833 is an inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), and used to treat diseases such as rheumatoid arthritis, lupus, and lymphomas.

Name PF06650833
Synonyms 1-{[(2S,3S,4S)-3-Ethyl-4-fluoro-5-oxo-2-pyrrolidinyl]methoxy}-7-methoxy-6-isoquinolinecarboxamide
S3F315JJXI
6-Isoquinolinecarboxamide, 1-[[(2S,3S,4S)-3-ethyl-4-fluoro-5-oxo-2-pyrrolidinyl]methoxy]-7-methoxy-
Description PF06650833 is an inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), and used to treat diseases such as rheumatoid arthritis, lupus, and lymphomas.
Related Catalog
References

[1]. Seganish WM. Inhibitors of interleukin-1 receptor-associated kinase 4 (IRAK4): a patent review (2012-2015). Expert Opin Ther Pat. 2016 Aug;26(8):917-32.

Density 1.3±0.1 g/cm3
Boiling Point 621.0±55.0 °C at 760 mmHg
Molecular Formula C18H20FN3O4
Molecular Weight 361.367
Flash Point 329.4±31.5 °C
Exact Mass 361.143799
LogP 0.19
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.607
Storage condition 2-8℃