37951-13-6

37951-13-6 structure

Name: Flavokawain A
Chemical Name: Flavokawain A
CAS Number: 37951-13-6
Molecular Formula: C₁₈H₁₈O₅
Molecular Weight: 314.332
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2018-01-31 23:11:29
Modify Date: 2024-01-10 16:15:29
Flavokawain A, a chalcone extracted from Kava, has anticarcinogenic effect. Flavokawain A induces apoptosis in bladder cancer cells by involvement of bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice[1].

Name	Flavokawain A
Synonyms	(2E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one (2E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one 1OR CQ EO1 BV1U1R DO1 &&E Form 2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-, (2E)- MFCD00017174 (E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one 2′-Hydroxy-4,4′,6′-trimethoxychalcone

Description	Flavokawain A, a chalcone extracted from Kava, has anticarcinogenic effect. Flavokawain A induces apoptosis in bladder cancer cells by involvement of bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
References	[1]. Zi X, et al. Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice. Cancer Res. 2005 Apr 15;65(8):3479-86.