186611-04-1
186611-04-1 structure
- Name: SU5214
- Chemical Name: SU 5214
- CAS Number: 186611-04-1
- Molecular Formula: C16H13NO2
- Molecular Weight: 251.280
- Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK VEGFR
- Create Date: 2018-07-03 13:22:19
- Modify Date: 2024-01-22 17:08:31
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SU5214 is a potent VEGFR2 inhibitor extracted from patent US5834504A, SU5214, has the IC50s of 14.8 µM (FLK-1) and 36.7 µM (EGFR), respectively[1].
| Name | SU 5214 |
|---|---|
| Synonyms |
2H-Indol-2-one, 1,3-dihydro-3-[(2-methoxyphenyl)methylene]-, (3Z)-
3-(2-methoxybenzylidene)indolin-2-one (3Z)-3-(2-Methoxybenzylidene)-1,3-dihydro-2H-indol-2-one |
| Description | SU5214 is a potent VEGFR2 inhibitor extracted from patent US5834504A, SU5214, has the IC50s of 14.8 µM (FLK-1) and 36.7 µM (EGFR), respectively[1]. |
|---|---|
| Related Catalog | |
| Target |
Flk-1:14.8 μM (IC50) |
| References |
[1]. Tang et al. 3-(2'-halobenzylidenyl)-2-indolinone compounds for the treatment of disease. US5834504A. |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 469.4±45.0 °C at 760 mmHg |
| Molecular Formula | C16H13NO2 |
| Molecular Weight | 251.280 |
| Flash Point | 237.7±28.7 °C |
| Exact Mass | 251.094635 |
| LogP | 3.42 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.657 |
| Storage condition | -20℃ |