183598-56-3

183598-56-3 structure
183598-56-3 structure
  • Name: Leptin (22-56) (human)
  • Chemical Name: Leptin (22-56) (human)
  • CAS Number: 183598-56-3
  • Molecular Formula: C171H298N50O56
  • Molecular Weight: 3950.52
  • Catalog: Peptides
  • Create Date: 2018-05-20 08:00:00
  • Modify Date: 2025-08-25 12:00:59
  • Leptin (22-56), human is the fragment of leptin, mediated via several isoforms of receptors (Ob-Rs).

Name Leptin (22-56) (human)
Synonyms Val-Pro-Ile-Gln-Lys-Val-Gln-Asp-Asp-Thr-Lys-Thr-Leu-Ile-Lys-Thr-Ile-Val-Thr-Arg-Ile-Asn-Asp-Ile-Ser-His-Thr-Gln-Ser-Val-Ser-Ser-Lys-Gln-Lys
Description Leptin (22-56), human is the fragment of leptin, mediated via several isoforms of receptors (Ob-Rs).
Related Catalog
Target

Ob-Rs[1]

In Vitro Leptin (22-56), human is the fragment of leptin, inhibits corticosterone production, but shows no effect on the proliferation of cultured adrenocortical cells. Leptin (22-56) may be responsible for the direct inhibitory effect on secretion and growth of leptin on cultured rat adrenocortical cells[1]. Leptin (22-56) inhibits food intake, and may favour erythropoiesis[2].
References

[1]. Malendowicz LK, et al. Effects of leptin and leptin fragments on corticosterone secretion and growth of cultured rat adrenocortical cells. Int J Mol Med. 2004 Nov;14(5):873-7.

[2]. Stamatiadis DN, et al. Elevated leptin fragments in renal failure correlate with BMI and haematopoiesis and are normalized by haemodialysis. Clin Endocrinol (Oxf). 2004 Apr;60(4):434-41.

Molecular Formula C171H298N50O56
Molecular Weight 3950.52
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.