112199-06-1

112199-06-1 structure

Name: Prepro-Atrial Natriuretic Factor (56-92) (human) trifluoroacetate salt
Chemical Name: Prepro-Atrial Natriuretic Factor (56-92) (human)
CAS Number: 112199-06-1
Molecular Formula: C₃₁H₃₂N₄O₂
Molecular Weight: 492.611
Catalog: Signaling Pathways GPCR/G Protein Guanylate Cyclase
Create Date: 2018-05-21 08:00:00
Modify Date: 2024-01-02 10:23:37
Prepro-ANF (56-92), human is a human atrial natriuretic factor precursor. Prepro-ANF (56-92), human is also a Guanylate Cyclase activator that enhances particulate Guanylate Cyclase activity in the renal membrane and renal unit[1].

Name	Prepro-Atrial Natriuretic Factor (56-92) (human)
Synonyms	Benzamide, N-[3-[3-[(cyclopropylcarbonyl)amino]-7-isoquinolinyl]-4-methylphenyl]-4-[1-(dimethylamino)ethyl]- N-(3-{3-[(Cyclopropylcarbonyl)amino]-7-isoquinolinyl}-4-methylphenyl)-4-[1-(dimethylamino)ethyl]benzamide

Description	Prepro-ANF (56-92), human is a human atrial natriuretic factor precursor. Prepro-ANF (56-92), human is also a Guanylate Cyclase activator that enhances particulate Guanylate Cyclase activity in the renal membrane and renal unit[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Guanylate Cyclase
In Vitro	Prepro-ANF (56-92), human (1 µM; 10 min) enhances particulate guanylate cyclase from 105,000 g whole kidney homogenates, renal cortical and medullary membranes, and in the isolated distal nephrons[1].
References	[1]. Vesely DL, et al. Human prepro atrial natriuretic factors 26-55, 56-92, and 104-123 increase renal guanylate cyclase activity. Biochem Biophys Res Commun. 1987 Feb 27;143(1):186-93.