1434048-34-6
1434048-34-6 structure
- Name: GDC-0853
- Chemical Name: GDC0853
- CAS Number: 1434048-34-6
- Molecular Formula: C37H44N8O4
- Molecular Weight: 664.797
- Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK Btk
- Create Date: 2018-04-07 21:01:17
- Modify Date: 2025-08-27 16:30:26
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GDC-0853 is a potent, selective, and noncovalent bruton's tyrosine kinase (Btk) inhibitor with a Ki of 0.91 nM.
| Name | GDC0853 |
|---|---|
| Synonyms |
2-[3'-(Hydroxymethyl)-1-methyl-5-({5-[(2S)-2-methyl-4-(3-oxetanyl)-1-piperazinyl]-2-pyridinyl}amino)-6-oxo-1,6-dihydro-3,4'-bipyridin-2'-yl]-7,7-dimethyl-3,4,7,8-tetrahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one
2H-Cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one, 2-[1,6-dihydro-3'-(hydroxymethyl)-1-methyl-5-[[5-[(2S)-2-methyl-4-(3-oxetanyl)-1-piperazinyl]-2-pyridinyl]amino]-6-oxo[3,4'-bipyridin]-2'-yl]-3,4,7,8-tetrahydro-7,7-dimethyl- GDC-0853 |
| Description | GDC-0853 is a potent, selective, and noncovalent bruton's tyrosine kinase (Btk) inhibitor with a Ki of 0.91 nM. |
|---|---|
| Related Catalog |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 936.3±65.0 °C at 760 mmHg |
| Molecular Formula | C37H44N8O4 |
| Molecular Weight | 664.797 |
| Flash Point | 520.0±34.3 °C |
| Exact Mass | 664.348572 |
| LogP | 1.59 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.725 |