1784751-19-4

1784751-19-4 structure

Name: TA-02
Chemical Name: TA-02
CAS Number: 1784751-19-4
Molecular Formula: C₂₀H₁₃F₂N₃
Molecular Weight: 333.334
Catalog: Signaling Pathways MAPK/ERK Pathway p38 MAPK
Create Date: 2018-04-07 18:48:29
Modify Date: 2025-08-24 22:50:19
TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.IC50 value: 20 nMTarget: p38TA-02 is a novel compound with similar cardiogenic properties asSB203580 and SB202190. TA-02 especially inhibits TGFBR-2.

Name	TA-02
Synonyms	Pyridine, 4-[2-(2-fluorophenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]- 4-[2-(2-Fluorophenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]pyridine

Description	TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.IC50 value: 20 nMTarget: p38TA-02 is a novel compound with similar cardiogenic properties asSB203580 and SB202190. TA-02 especially inhibits TGFBR-2.
Related Catalog	Signaling Pathways >> MAPK/ERK Pathway >> p38 MAPK Research Areas >> Cancer
References	[1]. Laco F, et al. Cardiomyocyte differentiation of pluripotent stem cells with SB203580 analogues correlates with Wnt pathway CK1 inhibition independent of p38 MAPK signaling. J Mol Cell Cardiol. 2015 Mar;80:56-70. [2]. Filip LACO, et al. 2,4,5-tri-substituted azole-based casein kinase 1 inhibitors as inducers for cardiomyogenesis. WO 2015119579 A1.