574013-67-5
574013-67-5 structure
- Name: Fexarine
- Chemical Name: (E)-methyl 3-(3-(N-(4-(benzo[d][1,3]dioxol-5-yl)benzyl)cyclohexanecarboxamido)phenyl)acrylate
- CAS Number: 574013-67-5
- Molecular Formula: C31H31NO5
- Molecular Weight: 497.58
- Catalog: Signaling Pathways Metabolic Enzyme/Protease FXR
- Create Date: 2018-03-02 21:56:01
- Modify Date: 2025-08-25 08:08:34
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Fexarine is a potent, non-steroidal and selective agonist of farnesoid X receptor (EC50: 38 nM). Fexarine can be used for the research of diseases linked to cholesterol, bile acids[1].
| Name | (E)-methyl 3-(3-(N-(4-(benzo[d][1,3]dioxol-5-yl)benzyl)cyclohexanecarboxamido)phenyl)acrylate |
|---|---|
| Synonyms |
2-Propenoic acid, 3-[3-[[[4-(1,3-benzodioxol-5-yl)phenyl]methyl](cyclohexylcarbonyl)amino]phenyl]-, methyl ester, (2E)-
MFCD29035146 methyl (2E)-3-(3-{[4-(1,3-benzodioxol-5-yl)benzyl](cyclohexylcarbonyl)amino}phenyl)prop-2-enoate Methyl (2E)-3-(3-{[4-(1,3-benzodioxol-5-yl)benzyl](cyclohexylcarbonyl)amino}phenyl)acrylate Fexarine |
| Description | Fexarine is a potent, non-steroidal and selective agonist of farnesoid X receptor (EC50: 38 nM). Fexarine can be used for the research of diseases linked to cholesterol, bile acids[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Fexarine (1 μM) 诱导 HT29-FXRFL 细胞中 IBABP mRNA 的表达[1]。 |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 681.2±55.0 °C at 760 mmHg |
| Molecular Formula | C31H31NO5 |
| Molecular Weight | 497.58 |
| Flash Point | 365.8±31.5 °C |
| Exact Mass | 497.220215 |
| LogP | 6.34 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.634 |