654059-21-9

654059-21-9 structure
654059-21-9 structure
  • Name: HSL-IN-2
  • Chemical Name: 4-Isopropyl-3-methyl-2-{[(3S)-3-methyl-1-piperidinyl]carbonyl}-1,2-oxazol-5(2H)-one
  • CAS Number: 654059-21-9
  • Molecular Formula: C14H22N2O3
  • Molecular Weight: 266.336
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2018-05-31 06:50:58
  • Modify Date: 2025-08-22 17:45:20
  • HSL-IN-2 is a potent and selective inhibitor of Hormone Sensitive Lipase (HSL), with an IC50 of 0.023 μM.

Name 4-Isopropyl-3-methyl-2-{[(3S)-3-methyl-1-piperidinyl]carbonyl}-1,2-oxazol-5(2H)-one
Synonyms 4-Isopropyl-3-methyl-2-{[(3S)-3-methyl-1-piperidinyl]carbonyl}-1,2-oxazol-5(2H)-one
3-methyl-2-{[(3S)-3-methylpiperidin-1-yl]carbonyl}-4-(propan-2-yl)-1,2-oxazol-5(2H)-one
5(2H)-Isoxazolone, 3-methyl-4-(1-methylethyl)-2-[[(3S)-3-methyl-1-piperidinyl]carbonyl]-
Piperidine,3-methyl-1-[[3-methyl-4-(1-methylethyl)-5-oxo-2(5H)-isoxazolyl]carbonyl]-,(3S)-(9CI
Description HSL-IN-2 is a potent and selective inhibitor of Hormone Sensitive Lipase (HSL), with an IC50 of 0.023 μM.
Related Catalog
Target

IC50: 0.023 μM (HSL)[1].

References

[1]. Ebdrup S, et al. Synthesis and structure-activity relationship for a novel class of potent and selective carbamoyl-triazole based inhibitors of hormone sensitive lipase. J Med Chem. 2004 Jan 15;47(2):400-10.

Density 1.1±0.1 g/cm3
Boiling Point 345.8±25.0 °C at 760 mmHg
Molecular Formula C14H22N2O3
Molecular Weight 266.336
Flash Point 162.9±23.2 °C
Exact Mass 266.163055
LogP 2.42
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.522
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