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1404111-67-6

1404111-67-6 structure
1404111-67-6 structure
  • Name: N-Boc-PEG5-alcohol
  • Chemical Name: 2-Methyl-2-propanyl (14-hydroxy-3,6,9,12-tetraoxatetradec-1-yl)carbamate
  • CAS Number: 1404111-67-6
  • Molecular Formula: C15H31NO7
  • Molecular Weight: 337.409
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-01 23:22:04
  • Modify Date: 2024-01-09 17:34:09
  • N-Boc-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 2-Methyl-2-propanyl (14-hydroxy-3,6,9,12-tetraoxatetradec-1-yl)carbamate
Synonyms 2-Methyl-2-propanyl (14-hydroxy-3,6,9,12-tetraoxatetradec-1-yl)carbamate
Carbamic acid, N-(14-hydroxy-3,6,9,12-tetraoxatetradec-1-yl)-, 1,1-dimethylethyl ester
Description N-Boc-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Boiling Point 451.5±40.0 °C at 760 mmHg
Molecular Formula C15H31NO7
Molecular Weight 337.409
Flash Point 226.8±27.3 °C
Exact Mass 337.210052
LogP -0.67
Vapour Pressure 0.0±2.5 mmHg at 25°C
Index of Refraction 1.461
Storage condition -20°C