1395786-30-7
1395786-30-7 structure
- Name: DBCO-Maleimide
- Chemical Name: N-[3-(11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl)-3-oxopropyl]-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide
- CAS Number: 1395786-30-7
- Molecular Formula: C25H21N3O4
- Molecular Weight: 427.452
- Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
- Create Date: 2018-02-27 14:43:21
- Modify Date: 2024-01-02 16:35:29
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DBCO-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
| Name | N-[3-(11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl)-3-oxopropyl]-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide |
|---|---|
| Synonyms |
1H-Pyrrole-1-propanamide, N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]-2,5-dihydro-2,5-dioxo-
N-[3-(11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl)-3-oxopropyl]-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide |
| Description | DBCO-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
|---|---|
| Related Catalog | |
| Target |
Cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
| References |
[1]. Modified antibody and radioactive metal-labelled antibody. WO2019203191A1. |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 790.5±60.0 °C at 760 mmHg |
| Molecular Formula | C25H21N3O4 |
| Molecular Weight | 427.452 |
| Flash Point | 431.9±32.9 °C |
| Exact Mass | 427.153198 |
| LogP | 3.10 |
| Vapour Pressure | 0.0±2.8 mmHg at 25°C |
| Index of Refraction | 1.688 |
| Storage condition | -20°C |