75970-99-9

75970-99-9 structure

Name: norastemizole
Chemical Name: 1-[(4-fluorophenyl)methyl]-N-piperidin-4-ylbenzimidazol-2-amine
CAS Number: 75970-99-9
Molecular Formula: C₁₉H₂₁FN₄
Molecular Weight: 324.40
Catalog: Signaling Pathways GPCR/G Protein Histamine Receptor
Create Date: 2017-04-22 17:06:30
Modify Date: 2025-08-26 16:22:10
Tecastemizole (Norastemizole), a major metabolite of Astemizole, is a potent and selective H1 receptor antagonist. Tecastemizole shows anti-inflammatory activities[1].

Name	1-[(4-fluorophenyl)methyl]-N-piperidin-4-ylbenzimidazol-2-amine
Synonyms	T 1348 Tetemizole Soltara Norastemizole

Description	Tecastemizole (Norastemizole), a major metabolite of Astemizole, is a potent and selective H1 receptor antagonist. Tecastemizole shows anti-inflammatory activities[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Histamine Receptor
References	[1]. Lever R, et al. Effect of tecastemizole on pulmonary and cutaneous allergic inflammatory responses. Clin Exp Allergy. 2007 Jun;37(6):909-17.