1215631-57-4

1215631-57-4 structure
1215631-57-4 structure
  • Name: Iprodione-d5
  • Chemical Name: 3-[3,5-Dichloro(2H3)phenyl]-N-isopropyl-2,4-dioxo(2H2)imidazolidine-1-carboxamide
  • CAS Number: 1215631-57-4
  • Molecular Formula: C13H8D5Cl2N3O3
  • Molecular Weight: 335.197
  • Catalog: Signaling Pathways Anti-infection Fungal
  • Create Date: 2018-05-10 14:06:43
  • Modify Date: 2024-02-06 21:03:30
  • Iprodione-d5 is the deuterium labeled Iprodione[1]. Iprodione, a dicarboximide fungicide, has a highly specific action, with a capacity to cause oxidative damage through production of free oxygen radicals (ROS). Iprodione does not appear to be species selective[2].

Name 3-[3,5-Dichloro(2H3)phenyl]-N-isopropyl-2,4-dioxo(2H2)imidazolidine-1-carboxamide
Synonyms 3-[3,5-Dichloro(H)phenyl]-N-isopropyl-2,4-dioxo(H)imidazolidine-1-carboxamide
1-Imidazolidine-5,5-d-carboxamide, 3-(3,5-dichlorophenyl-2,4,6-d)-N-(1-methylethyl)-2,4-dioxo-
3-[3,5-Dichloro(H)phenyl]-N-isopropyl-2,4-dioxo-1-(H)imidazolidinecarboxamide
Description Iprodione-d5 is the deuterium labeled Iprodione[1]. Iprodione, a dicarboximide fungicide, has a highly specific action, with a capacity to cause oxidative damage through production of free oxygen radicals (ROS). Iprodione does not appear to be species selective[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Radice S, et al. Effect of iprodione, a dicarboximide fungicide, on primary cultured rainbow trout (Oncorhynchus mykiss) hepatocytes. Aquat Toxicol. 2001;54(1-2):51-58.  

Density 1.5±0.1 g/cm3
Molecular Formula C13H8D5Cl2N3O3
Molecular Weight 335.197
Exact Mass 334.064789
LogP 2.80
Index of Refraction 1.604