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1793053-37-8

1793053-37-8 structure
1793053-37-8 structure
  • Name: LLY 507
  • Chemical Name: LLY-507
  • CAS Number: 1793053-37-8
  • Molecular Formula: C36H42N6O
  • Molecular Weight: 574.758
  • Catalog: Signaling Pathways Epigenetics Histone Methyltransferase
  • Create Date: 2018-04-28 09:28:29
  • Modify Date: 2024-01-02 14:13:43
  • LLY-507 is a potent and selective inhibitor of protein-lysine methyltransferase SMYD2 with an IC50 of 15 nM.

Name LLY-507
Synonyms 5-Cyano-2'-{4-[2-(3-methyl-1H-indol-1-yl)ethyl]-1-piperazinyl}-N-[3-(1-pyrrolidinyl)propyl]-3-biphenylcarboximidic acid
[1,1'-Biphenyl]-3-carboximidic acid, 5-cyano-2'-[4-[2-(3-methyl-1H-indol-1-yl)ethyl]-1-piperazinyl]-N-[3-(1-pyrrolidinyl)propyl]-
Description LLY-507 is a potent and selective inhibitor of protein-lysine methyltransferase SMYD2 with an IC50 of 15 nM.
Related Catalog
References

[1]. Nguyen H, et al. LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2. J Biol Chem. 2015 May 29;290(22):13641-13653.

Density 1.2±0.1 g/cm3
Boiling Point 790.4±70.0 °C at 760 mmHg
Molecular Formula C36H42N6O
Molecular Weight 574.758
Flash Point 431.8±35.7 °C
Exact Mass 574.341980
LogP 7.27
Vapour Pressure 0.0±2.9 mmHg at 25°C
Index of Refraction 1.646
Storage condition -20℃