945553-91-3
945553-91-3 structure
- Name: (R,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
- Chemical Name: (2E)-N-{4-[(3-Chloro-4-fluorophenyl)amino]-7-[(3R)-tetrahydro-3-furanyloxy]-6-quinazolinyl}-4-(dimethylamino)-2-butenamide
- CAS Number: 945553-91-3
- Molecular Formula: C24H25ClFN5O3
- Molecular Weight: 485.938
- Create Date: 2018-02-19 08:00:00
- Modify Date: 2023-01-01 19:54:49
| Name | (2E)-N-{4-[(3-Chloro-4-fluorophenyl)amino]-7-[(3R)-tetrahydro-3-furanyloxy]-6-quinazolinyl}-4-(dimethylamino)-2-butenamide |
|---|---|
| Synonyms |
2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3R)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-, (2E)-
(2E)-N-{4-[(3-Chloro-4-fluorophenyl)amino]-7-[(3R)-tetrahydro-3-furanyloxy]-6-quinazolinyl}-4-(dimethylamino)-2-butenamide (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3R)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide Afatinib Impurity 3 |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 676.9±55.0 °C at 760 mmHg |
| Molecular Formula | C24H25ClFN5O3 |
| Molecular Weight | 485.938 |
| Flash Point | 363.2±31.5 °C |
| Exact Mass | 485.162994 |
| LogP | 3.59 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.668 |
| Water Solubility | Insuluble (7.3E-5 g/L) (25 ºC) |