Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Chicanine
Price: Check
Purity: 99.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 4-[(2R,3S,4R,5R)-5-(1,3-Benzodioxol-5-yl)tetrahydro-3,4-dimethyl-2-furanyl]-2-methoxyphenol
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

78919-28-5

78919-28-5 structure

78919-28-5 structure

Name: Chicanine
Chemical Name: (+)-chicanine
CAS Number: 78919-28-5
Molecular Formula: C₂₀H₂₂O₅
Molecular Weight: 342.386
Catalog: Signaling Pathways MAPK/ERK Pathway ERK
Create Date: 2018-08-27 10:29:52
Modify Date: 2025-08-25 11:30:42
Chicanine is a lignan compound of Schisandra chinesis, inhibits LPS-induced phosphorylation of p38 MAPK, ERK 1/2 and IκB-α, with anti-inflammatory activity[1].

Name	(+)-chicanine
Synonyms	Phenol, 4-[(2S,3R,4S,5S)-5-(1,3-benzodioxol-5-yl)tetrahydro-3,4-dimethyl-2-furanyl]-2-methoxy- 4-[(2S,3R,4S,5S)-5-(1,3-Benzodioxol-5-yl)-3,4-dimethyltetrahydro-2-furanyl]-2-methoxyphenol chicanine 4-((2S,3R,4S,5S)-5-Benzo[1,3]dioxol-5-yl-3,4-dimethyl-tetrahydro-furan-2-yl)-2-methoxy-phenol Chicanin

Description	Chicanine is a lignan compound of Schisandra chinesis, inhibits LPS-induced phosphorylation of p38 MAPK, ERK 1/2 and IκB-α, with anti-inflammatory activity[1].
Related Catalog	Signaling Pathways >> NF-κB >> IKK Signaling Pathways >> MAPK/ERK Pathway >> p38 MAPK Research Areas >> Inflammation/Immunology Signaling Pathways >> MAPK/ERK Pathway >> ERK Signaling Pathways >> Stem Cell/Wnt >> ERK
References	[1]. Chicanine, et al. Anti-inflammatory effects of chicanine on murine macrophage by down-regulating LPS-induced inflammatory cytokines in IκBα/MAPK/ERK signaling pathways. Eur J Pharmacol. 2014 Feb 5;724:168-74.

Density	1.2±0.1 g/cm3
Boiling Point	483.8±45.0 °C at 760 mmHg
Molecular Formula	C₂₀H₂₂O₅
Molecular Weight	342.386
Flash Point	246.4±28.7 °C
Exact Mass	342.146729
PSA	57.15000
LogP	3.88
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.575

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