Top Suppliers:I want be here

1263166-90-0

1263166-90-0 structure
1263166-90-0 structure
  • Name: Endo-BCN-Nitrobenzene
  • Chemical Name: BCN alcohol
  • CAS Number: 1263166-90-0
  • Molecular Formula: C10H14O
  • Molecular Weight: 150.21800
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-01-06 02:10:20
  • Modify Date: 2024-01-31 17:41:59
  • Endo-BCN-Nitrobenzene is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name BCN alcohol
Synonyms BCN
(1R,8S,9ξ)-bicyclo[6.1.0]non-4-yn-9-ylmethanol
(1R,8S,9S)-bicyclo[6.1.0]non-4-yn-9-ylmethanol
BCN-OH
BCNM
(1R,8S,9s)-bicyclo[6.1.0]non-4-yne-9-ylmethanol
Description Endo-BCN-Nitrobenzene is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C10H14O
Molecular Weight 150.21800
Exact Mass 150.10400
PSA 20.23000
LogP 1.41830
Storage condition -20°C
RIDADR NONH for all modes of transport