918132-14-6

918132-14-6 structure

Name: T-Boc-aminoxy-peg4-alcohol
Chemical Name: T-Boc-aminoxy-peg4-alcohol
CAS Number: 918132-14-6
Molecular Formula: C₁₃H₂₇NO₇
Molecular Weight: 309.35600
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-02-21 16:57:39
Modify Date: 2025-08-20 19:11:50
Boc-Aminoxy-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	T-Boc-aminoxy-peg4-alcohol
Synonyms	MFCD28064334

Description	Boc-Aminoxy-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562