71030-36-9

71030-36-9 structure

Name: (±)15-HETE
Chemical Name: (+/-)-15-hete
CAS Number: 71030-36-9
Molecular Formula: C₂₀H₃₂O₃
Molecular Weight: 320.466
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-03-06 08:53:42
Modify Date: 2025-08-31 18:33:45
(±)15-HETE is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	(+/-)-15-hete
Synonyms	5,8,11,13-eicosatetraenoic acid, 15-hydroxy-, (5Z,8Z,11Z)- (5Z,8Z,11Z,13E)-15-Hydroxy-icosa-5,8,11,13-tetraenoic acid 5,8,11,13-Eicosatetraenoic acid, 15-hydroxy-, (5Z,8Z,11Z,13E)- (5Z,8Z,11Z,13E)-15-Hydroxy-5,8,11,13-icosatetraenoic acid 15-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid (Z,Z,Z,E)-15-hydroxyeicosa-5,8,11,13-tetraenoic acid 15-hydroxyeicosatetraenoic acid 15-HETE 15-hydroxyeicosa-5Z,8Z,11Z,13E-tetraenoic acid (5Z,8Z,11Z)-15-hydroxyicosa-5,8,11,13-tetraenoic acid (15S,5Z,8Z,11Z,13E)-15-hydroxyeicosatetraenoic acid

Description	(±)15-HETE is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl-Chain
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.