68030-18-2

68030-18-2 structure

Name: Berberine chloride hydrate
Chemical Name: berberine hydrochloride hydrate
CAS Number: 68030-18-2
Molecular Formula: C₂₀H₂₀ClNO₅
Molecular Weight: 389.83000
Catalog: Signaling Pathways Autophagy Autophagy
Create Date: 2018-06-18 02:27:35
Modify Date: 2025-08-20 09:30:58
Berberine chloride hydrate is an alkaloid in several plants with various biological functions, including insulin-sensitizing, anti-inflammatory, and anti-oxidant activity. Berberine chloride hydrate is an AMPK activator.

Name	berberine hydrochloride hydrate

Description	Berberine chloride hydrate is an alkaloid in several plants with various biological functions, including insulin-sensitizing, anti-inflammatory, and anti-oxidant activity. Berberine chloride hydrate is an AMPK activator.
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> β-catenin Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> Stem Cell/Wnt >> Wnt Research Areas >> Cancer
References	[1]. Albring KF, et al. Berberine acts as a natural inhibitor of Wnt/β-catenin signaling--identification of more active 13-arylalkyl derivatives. Biofactors. 2013 Nov-Dec;39(6):652-62. [2]. Jabbarzadeh Kaboli P, et al. Targets and mechanisms of berberine, a natural drug with potential to treat cancer with special focus on breast cancer. Eur J Pharmacol. 2014 Jun 26. pii: S0014-2999(14)00467-1. [3]. Wang Y, et al. Berberine decreases cholesterol levels in rats through multiple mechanisms, including inhibition of cholesterol absorption. Metabolism. 2014 Jun 4. pii: S0026-0495(14)00162-0. [4]. Yu R, et al. Berberine-induced apoptotic and autophagic death of HepG2 cells requires AMPK activation. Cancer Cell Int. 2014 Jun 11;14:49.