70222-95-6

70222-95-6 structure

Name: N,N-dimethyldoxorubicin
Chemical Name: nsc 261045
CAS Number: 70222-95-6
Molecular Formula: C₂₉H₃₃NO₁₁
Molecular Weight: 571.57200
Catalog: Research Areas Cancer
Create Date: 2018-03-27 06:12:44
Modify Date: 2024-11-28 08:07:23
N,N-Dimethyldoxorubicin is a Doxorubicin (HY-15142A) analogue. N,N-Dimethyldoxorubicin shows cytotoxicity against a panel of tumor cell lines (IC50s < 0.3 μM)[1].

Name	nsc 261045
Synonyms	(8S,10S)-10-((2R,4S,5S,6S)-4-Dimethylamino-5-hydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-6,8,11-trihydroxy-8-(2-hydroxy-acetyl)-1-methoxy-7,8,9,10-tetrahydro-naphthacene-5,12-dione

Description	N,N-Dimethyldoxorubicin is a Doxorubicin (HY-15142A) analogue. N,N-Dimethyldoxorubicin shows cytotoxicity against a panel of tumor cell lines (IC50s < 0.3 μM)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Wander DPA, et al. Synthetic (N,N-Dimethyl)doxorubicin Glycosyl Diastereomers to Dissect Modes of Action of Anthracycline Anticancer Drugs. J Org Chem. 2021 Apr 16;86(8):5757-5770.