112649-21-5

112649-21-5 structure

Name: Garcinone E
Chemical Name: garcinone E
CAS Number: 112649-21-5
Molecular Formula: C₂₈H₃₂O₆
Molecular Weight: 464.55000
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2018-04-12 08:00:00
Modify Date: 2025-09-02 13:31:12
Garcinone E is a natural xanthone found in the rind of the mangosteen fruit. Garcinone E induces apoptosis and inhibits cancer cell migration. Garcinone E has anticancer effects on different human cancer cell lines, including colorectal, breast, and hepatocellular carcinomas[1].

Name	garcinone E
Synonyms	garcinone-E 2,3,6,8-Tetrahydroxy-1,4,7-tris-(3-methyl-but-2-enyl)-xanthen-9-one

Description	Garcinone E is a natural xanthone found in the rind of the mangosteen fruit. Garcinone E induces apoptosis and inhibits cancer cell migration. Garcinone E has anticancer effects on different human cancer cell lines, including colorectal, breast, and hepatocellular carcinomas[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
References	[1]. Linli Yang, et al. Garcinone-E exhibits anticancer effects in HeLa human cervical carcinoma cells mediated via programmed cell death, cell cycle arrest and suppression of cell migration and invasion. AMB Express. 2020 Jul 16;10(1):126.