692739-25-6
692739-25-6 structure
- Name: 6-Maleimidocaproic acid-PFP ester
- Chemical Name: pentafluorophenyl 6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoate
- CAS Number: 692739-25-6
- Molecular Formula: C16H12F5NO4
- Molecular Weight: 377.26300
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-27 03:49:06
- Modify Date: 2024-01-03 11:45:18
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6-Maleimidocaproic acid-PFP ester is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | pentafluorophenyl 6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoate |
|---|---|
| Synonyms |
6-(2,5-Dioxo-2,5-dihydro-pyrrol-1-yl)-hexanoic acid pentafluorophenyl ester
6-maleimidohexanoic acid pentafluorophenyl ester pentafluorophenyl 6-maleimidohexanoate |
| Description | 6-Maleimidocaproic acid-PFP ester is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl-Chain |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C16H12F5NO4 |
|---|---|
| Molecular Weight | 377.26300 |
| Exact Mass | 377.06900 |
| PSA | 63.68000 |
| LogP | 2.71080 |