5580-27-8

MOLECULAR FORMULA :

C9-H17-Cl2-N-O2

MOLECULAR WEIGHT :

242.17

WISWESSER LINE NOTATION :

G3N3GVO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Human - woman

DOSE/DURATION :

405 mg/kg/27D

TOXIC EFFECTS :

Behavioral - analgesia Blood - leukopenia

REFERENCE :

CNCRA6 Cancer Chemotherapy Reports. (Bethesda, MD) V.1-52, 1959-68. For publisher information, see CTRRDO. Volume(issue)/page/year: 36,77,1964

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Human - man

DOSE/DURATION :

593 mg/kg/18D

TOXIC EFFECTS :

Gastrointestinal - nausea or vomiting

REFERENCE :

CNCRA6 Cancer Chemotherapy Reports. (Bethesda, MD) V.1-52, 1959-68. For publisher information, see CTRRDO. Volume(issue)/page/year: 36,77,1964

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

3 gm/kg

TOXIC EFFECTS :

Tumorigenic - active as anti-cancer agent

REFERENCE :

CNCRA6 Cancer Chemotherapy Reports. (Bethesda, MD) V.1-52, 1959-68. For publisher information, see CTRRDO. Volume(issue)/page/year: 36,77,1964