226927-89-5

226927-89-5 structure

Name: LB42908
Chemical Name: [1-{[1-(1,3-benzodioxole-5-ylmethyl)-1H-imidazole-5-yl]methyl}-4-(1-naphthyl)-1H-pyrrole-3yl](4-methyl-1-piperazinyl)methanone
CAS Number: 226927-89-5
Molecular Formula: C₃₂H₃₁N₅O₃
Molecular Weight: 533.62000
Create Date: 2018-02-24 13:35:24
Modify Date: 2025-08-31 06:57:41
LB42908 is a highly potent, selective, orally active inhibitor of Ras farnesyltransferase (FTase) with IC50 of 0.9 nM against H-Ras and 2.4 nM against K-Ras..

Name	[1-{[1-(1,3-benzodioxole-5-ylmethyl)-1H-imidazole-5-yl]methyl}-4-(1-naphthyl)-1H-pyrrole-3yl](4-methyl-1-piperazinyl)methanone
Synonyms	LB-42908 1-[1-(3,4-methylenedioxybenzyl)-1H-imidazol-5-ylmethyl]-3-(4-methylpiperazin-1-yl)carbonyl-4-(naphthalen-1-yl)-1H-pyrrole 1-[1-(3,4-methylenedioxybenzyl)-1H-imidazol-5-ylmethyl]-3-(4methylpiperazin-1-yl)carbonyl-4(naphthalen-1-yl)-1H-pyrrole