Name | 3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontane-1,35-diamine |
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Synonyms | 3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontane-1,35-diamine |
Description | Amino-PEG11-amine, a PEG-based (12 units) PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer[1]. |
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Related Catalog | |
Target |
PEGs |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
References |
Density | 1.1±0.1 g/cm3 |
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Boiling Point | 591.2±45.0 °C at 760 mmHg |
Molecular Formula | C24H52N2O11 |
Molecular Weight | 544.677 |
Flash Point | 299.9±22.4 °C |
Exact Mass | 544.357117 |
LogP | -4.81 |
Vapour Pressure | 0.0±1.7 mmHg at 25°C |
Index of Refraction | 1.468 |
Storage condition | 2-8°C |