9028-48-2

9028-48-2 structure

Name: Isocitrate dehydrogenase
Chemical Name: Isocitric dehydrogenase
CAS Number: 9028-48-2
Molecular Formula:
Molecular Weight:
Catalog: Signaling Pathways Metabolic Enzyme/Protease Isocitrate Dehydrogenase (IDH)
Create Date: 2019-02-17 02:18:57
Modify Date: 2025-08-24 21:45:45
Isocitrate dehydrogenase (ICDH) is a citric acid or tricarboxylic acid cycle enzyme, is often used in biochemical studies. Isocitrate dehydrogenase catalyzes the oxidative decarboxylation of isocitrate to α-ketoglutarate and reduces NAD(P)+ to NAD(P)H, it plays important roles in cellular metabolism[1].

Name	Isocitric dehydrogenase
Synonyms	NADP-specific isocitric dehydyrogenase NADPH-dependent isocitrate dehydrogenase Oxalosuccinic decarboxylase TPN-dependent isocitrate dehydrogenase TPN-isocitrate dehydrogenase TPN-linked isocitrate dehydrogenase TPN-specific isocitrate dehydrogenase

Description	Isocitrate dehydrogenase (ICDH) is a citric acid or tricarboxylic acid cycle enzyme, is often used in biochemical studies. Isocitrate dehydrogenase catalyzes the oxidative decarboxylation of isocitrate to α-ketoglutarate and reduces NAD(P)+ to NAD(P)H, it plays important roles in cellular metabolism[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Isocitrate Dehydrogenase (IDH) Research Areas >> Metabolic Disease
References	[1]. Reitman ZJ, Yan H. Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism. J Natl Cancer Inst. 2010 Jul 7;102(13):932-41.

Storage condition	2-8°C

Personal Protective Equipment	Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
RIDADR	NONH for all modes of transport