910-86-1
910-86-1 structure
- Name: Thiocarlide
- Chemical Name: 1,3-bis[4-(3-methylbutoxy)phenyl]thiourea
- CAS Number: 910-86-1
- Molecular Formula: C23H32N2O2S
- Molecular Weight: 400.577
- Catalog: Chemical reagent Organic reagent Thiourea
- Create Date: 2018-06-16 21:36:38
- Modify Date: 2024-01-12 21:59:14
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Thiocarlide (isoxyl) is a thiourea derivative that was used in the 1960s to successfully treat tuberculosis (TB).
| Name | 1,3-bis[4-(3-methylbutoxy)phenyl]thiourea |
|---|---|
| Synonyms |
Tiocarlida
4-13-00-01187 (Beilstein Handbook Reference) Sarbamyl Thiocarlide 1,3-Bis(p-isoamyloxyphenyl)-2-thiourea 4,4'-Di(isoamyloxy)thiocarbanilide Amixyl Tiocarlid DATC Thiourea, N,N'-bis[4-(3-methylbutoxy)phenyl]- Thiourea, N,N'-bis(4-(3-methylbutoxy)phenyl)- 1,3-Bis[4-(3-methylbutoxy)phenyl]thiourea Thiourea, N,N'-bis(4-(3-methylbutoxy)phenyl)- (9CI) Tiocarlidum Disoxyl tiocarlide N,N'-[4-(3-Methylbutoxy)phenyl]thiourea Isoxyl |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 508.5±60.0 °C at 760 mmHg |
| Melting Point | 134-145° |
| Molecular Formula | C23H32N2O2S |
| Molecular Weight | 400.577 |
| Flash Point | 261.3±32.9 °C |
| Exact Mass | 400.218445 |
| PSA | 74.61000 |
| LogP | 6.12 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.600 |
|
~50%
910-86-1 |
| Literature: Brown, Joshua R.; North, Elton J.; Hurdle, Julian G.; Morisseau, Christophe; Scarborough, Jerrod S.; Sun, Dianqing; Kordulakova, Jana; Scherman, Michael S.; Jones, Victoria; Grzegorzewicz, Anna; Crew, Rebecca M.; Jackson, Mary; McNeil, Michael R.; Lee, Richard E. Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 18 p. 5585 - 5595 |
|
~54%
910-86-1 |
| Literature: Bhowruth, Veemal; Brown, Alistair K.; Reynolds, Robert C.; Coxon, Geoffrey D.; Mackay, Simon P.; Minnikin, David E.; Besra, Gurdyal S. Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 18 p. 4743 - 4747 |
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~%
910-86-1 |
| Literature: Brown, Joshua R.; North, Elton J.; Hurdle, Julian G.; Morisseau, Christophe; Scarborough, Jerrod S.; Sun, Dianqing; Kordulakova, Jana; Scherman, Michael S.; Jones, Victoria; Grzegorzewicz, Anna; Crew, Rebecca M.; Jackson, Mary; McNeil, Michael R.; Lee, Richard E. Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 18 p. 5585 - 5595 |
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~%
910-86-1 |
| Literature: Brown, Joshua R.; North, Elton J.; Hurdle, Julian G.; Morisseau, Christophe; Scarborough, Jerrod S.; Sun, Dianqing; Kordulakova, Jana; Scherman, Michael S.; Jones, Victoria; Grzegorzewicz, Anna; Crew, Rebecca M.; Jackson, Mary; McNeil, Michael R.; Lee, Richard E. Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 18 p. 5585 - 5595 |
|
~%
910-86-1 |
| Literature: Brown, Joshua R.; North, Elton J.; Hurdle, Julian G.; Morisseau, Christophe; Scarborough, Jerrod S.; Sun, Dianqing; Kordulakova, Jana; Scherman, Michael S.; Jones, Victoria; Grzegorzewicz, Anna; Crew, Rebecca M.; Jackson, Mary; McNeil, Michael R.; Lee, Richard E. Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 18 p. 5585 - 5595 |
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~%
910-86-1 |
| Literature: CIBA Patent: US2703815 , 1951 ; Full Text Show Details CIBA Patent: DE923446 , 1952 ; |
