132489-69-1
132489-69-1 structure
- Name: PugNAc
- Chemical Name: O-(2-Acetamido-2-deoxy-D-glucopyranosylidene)amino N-Phenylcarbamate
- CAS Number: 132489-69-1
- Molecular Formula: C15H19N3O7
- Molecular Weight: 353.33
- Catalog: Research Areas Metabolic Disease
- Create Date: 2018-12-22 22:50:59
- Modify Date: 2025-08-20 11:12:20
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(Z)-PUGNAc is a potent O-GlcNAcase inhibitor. (Z)-PUGNAc is a vastly more potent inhibitor of O-GlcNAcase than the E form[1].
| Name | O-(2-Acetamido-2-deoxy-D-glucopyranosylidene)amino N-Phenylcarbamate |
|---|---|
| Synonyms |
(Z)-Pugnac,O-(2-Acetamido-2-deoxy-D-glucopyranosylidene)amino-Z-N-phenylcarbamate
O-(2-Acetamido-2-deoxy-D-glucopyranosylidenamino) N-phenylcarbamate |
| Description | (Z)-PUGNAc is a potent O-GlcNAcase inhibitor. (Z)-PUGNAc is a vastly more potent inhibitor of O-GlcNAcase than the E form[1]. |
|---|---|
| Related Catalog | |
| In Vitro | (Z)-PUGNAc amplifies the incorporation of O-GlcNAc on proteins within both HeLa and HEK cell systems[1]. |
| References |
| Density | 1.53g/cm3 |
|---|---|
| Melting Point | 172-175°C |
| Molecular Formula | C15H19N3O7 |
| Molecular Weight | 353.33 |
| Exact Mass | 353.12200 |
| PSA | 149.71000 |
| Index of Refraction | 1.638 |
| Storage condition | -20℃ |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
|
~71%
132489-69-1 |
| Literature: Mohan, Halasyam; Vasella, Andrea Helvetica Chimica Acta, 2000 , vol. 83, # 1 p. 114 - 118 |
|
~%
132489-69-1 |
| Literature: Helvetica Chimica Acta, , vol. 83, # 1 p. 114 - 118 |
|
~%
132489-69-1 |
| Literature: Helvetica Chimica Acta, , vol. 83, # 1 p. 114 - 118 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |