118506-26-6

118506-26-6 structure

Name: Myelin Basic Protein (87-99) (human, bovine, rat)
Chemical Name: Myelin Basic Protein (87-99)
CAS Number: 118506-26-6
Molecular Formula: C₇₄H₁₁₄N₂₀O₁₇
Molecular Weight: 1555.82000
Catalog: Research Areas Inflammation/Immunology
Create Date: 2018-12-28 13:43:28
Modify Date: 2024-01-11 20:20:39
Myelin Basic Protein(87-99) is an encephalitogenic peptide that induces basic protein-specific T cell proliferation. Myelin Basic Protein(87-99) causes a Th1 polarization in peripheral blood mononuclear cells with is implicated of multiple sclerosis (MS)[1][2].

Name	Myelin Basic Protein (87-99)
Synonyms	h-val-his-phe-phe-lys-asn-ile-val-thr-pro-arg-thr-pro-oh val-his-phe-phe-lys-asn-ile-val-thr-pro-arg-thr-pro vhffknivtprtp

Description	Myelin Basic Protein(87-99) is an encephalitogenic peptide that induces basic protein-specific T cell proliferation. Myelin Basic Protein(87-99) causes a Th1 polarization in peripheral blood mononuclear cells with is implicated of multiple sclerosis (MS)[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. R E Jones, et al. The synthetic 87-99 peptide of myelin basic protein is encephalitogenic in Buffalo rats. J Neuroimmunol. 1992 Apr;37(3):203-12. [2]. George Deraos, et al. Citrullination of linear and cyclic altered peptide ligands from myelin basic protein (MBP(87-99)) epitope elicits a Th1 polarized response by T cells isolated from multiple sclerosis patients: implications in triggering disease. J Med Chem. 2008 Dec 25;51(24):7834-42.