121695-87-2
121695-87-2 structure
- Name: Sarafotoxin C trifluoroacetate salt
- Chemical Name: Sarafotoxin S6c
- CAS Number: 121695-87-2
- Molecular Formula: C103H147N27O37S5
- Molecular Weight: 2515.75000
- Catalog: Signaling Pathways GPCR/G Protein Endothelin Receptor
- Create Date: 2018-09-27 08:16:46
- Modify Date: 2025-08-24 18:02:09
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Sarafotoxin S6c (SRTX-c) is a potent endothelin-B receptor agonist. Sarafotoxin S6c can cause vasoconstriction in both endothelium-intact and endothelium-denuded vessels[1].
| Name | Sarafotoxin S6c |
|---|---|
| Synonyms |
MFCD00133969
SRTX-c Sarafotoxin S 6c Sarafotoxin 6c |
| Description | Sarafotoxin S6c (SRTX-c) is a potent endothelin-B receptor agonist. Sarafotoxin S6c can cause vasoconstriction in both endothelium-intact and endothelium-denuded vessels[1]. |
|---|---|
| Related Catalog | |
| Target |
Endothelin-B receptor[1] |
| In Vivo | Sarafotoxin S6c can cause vasoconstriction in both endothelium-intact and endothelium-denuded vessels[1]. Animal Model: Male Wister rats, exposed to 10% O2 [chronic hypoxic (CH) rats] or room air (control rats) for 2 weeks[1] Dosage: 1 pM-1 mM Administration: Result: Chronic hypoxia had effect on the sensitivity of the main pulmonary arteries to SCS6c, and small vasoconstrictor responses to were evident. Caused vasoconstriction with a maximum response 30% of that to ET-1 in both endothelium-intact and endothelium-denuded vessels. |
| Molecular Formula | C103H147N27O37S5 |
|---|---|
| Molecular Weight | 2515.75000 |
| Exact Mass | 2513.91000 |
| PSA | 1172.52000 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |