2156-27-6

2156-27-6 structure

2156-27-6 structure

Name: benproperine
Chemical Name: benproperine
CAS Number: 2156-27-6
Molecular Formula: C₂₁H₂₇NO
Molecular Weight: 309.44500
Catalog: API Respiratory medication Antitussive
Create Date: 2018-03-01 08:00:00
Modify Date: 2024-01-09 14:06:02

Name	benproperine
Synonyms	1-O-Benzylphenoxy-2-piperidinopropan pirexyl Benproperin

Density	1.04g/cm3
Boiling Point	433ºC at 760mmHg
Molecular Formula	C₂₁H₂₇NO
Molecular Weight	309.44500
Flash Point	126.8ºC
Exact Mass	309.20900
PSA	12.47000
LogP	4.46850
Index of Refraction	1.5614 (estimate)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TN1304000

CHEMICAL NAME :: Piperidine, 1-(1-methyl-2-((alpha-phenyl-o-tolyl)oxy)ethyl)-

CAS REGISTRY NUMBER :: 2156-27-6

BEILSTEIN REFERENCE NO. :: 1258822

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C21-H27-N-O

MOLECULAR WEIGHT :: 309.49

WISWESSER LINE NOTATION :: T6NTJ AY1&1OR B1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1087 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 109,476,1970 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 6 gm/kg

SEX/DURATION :: female 60 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 109,476,1970

HS Code	2933399090

28994-41-4 structure

28994-41-4

~%

2156-27-6 structure

2156-27-6

Literature: Korea Research Institute of Bioscience and Biotechnology; KWON, Byoung Mog; HAN, Dong Cho; SHIN, Dae Seop; HAN, Young Min Patent: EP2638910 A2, 2013 ;

Precursor 1
28994-41-4
DownStream 0

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%