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26750-81-2

26750-81-2 structure
26750-81-2 structure
  • Name: Alibendol
  • Chemical Name: 2-hydroxy-N-(2-hydroxyethyl)-3-methoxy-5-prop-2-enylbenzamide
  • CAS Number: 26750-81-2
  • Molecular Formula: C13H17NO4
  • Molecular Weight: 251.278
  • Catalog: API Digestive system medication Biliary medicine
  • Create Date: 2018-03-06 08:00:00
  • Modify Date: 2024-01-02 11:58:10
  • Alibendol is an antispasmodic,choleretic, and cholekinetic. Target: Othersadministration of alibendol in beagle dogs, observed retention times were approximately 5.0 min for alibendol. The within-run precision showed RSD values between 5.83 and 16.96 %. The between-run RSD values varied from 6.73 to 17.99 % at the LLOQ [1].
Name 2-hydroxy-N-(2-hydroxyethyl)-3-methoxy-5-prop-2-enylbenzamide
Synonyms 2-Hydroxy-3-methoxy-5-allyl-N-(b-hydroxyethyl)benzamide
MFCD00865165
EINECS 247-960-9
Cebera
2-Hydroxy-N-(2-hydroxyethyl)-3-methoxy-5-(2-propenyl)benzamide
5-Allyl-2-hydroxy-N-(2-hydroxyethyl)-3-methoxybenzamide
5-Allyl-2-hydroxy-N-(2-hydroxyethyl)-m-anisamide
FC 54
Benzamide, 2-hydroxy-N-(2-hydroxyethyl)-3-methoxy-5-(2-propen-1-yl)-
2-Hydroxy-N-(2-hydroxyethyl)-3-methoxy-5-(prop-2-en-1-yl)benzolcarboxamid
Alibendol
Description Alibendol is an antispasmodic,choleretic, and cholekinetic. Target: Othersadministration of alibendol in beagle dogs, observed retention times were approximately 5.0 min for alibendol. The within-run precision showed RSD values between 5.83 and 16.96 %. The between-run RSD values varied from 6.73 to 17.99 % at the LLOQ [1].
Related Catalog
References

[1]. Sheng, L., H. Chen, and Y. Li, A HPLC method for determination of nicousamide in dog plasma and its application to pharmacokinetic studies. J Chromatogr B Analyt Technol Biomed Life Sci, 2007. 854(1-2): p. 99-103.
Density 1.2±0.1 g/cm3
Boiling Point 402.4±45.0 °C at 760 mmHg
Melting Point 98-101ºC
Molecular Formula C13H17NO4
Molecular Weight 251.278
Flash Point 197.2±28.7 °C
Exact Mass 251.115753
PSA 78.79000
LogP 1.15
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.564
Storage condition Refrigerator

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CU8730000
CHEMICAL NAME :
Benzamide, 5-allyl-2-hydroxy-N-(2-hydroxyethyl)-3-methoxy-
CAS REGISTRY NUMBER :
26750-81-2
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C13-H17-N-O4
MOLECULAR WEIGHT :
251.31
WISWESSER LINE NOTATION :
Q2MVR BQ CO1 E2U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CHTPBA Chimica Therapeutica. (Paris, France) V.1-8, 1965-73. For publisher information, see EJMCA5. Volume(issue)/page/year: 5,188,1970
HS Code 2924299090
HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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